Letrozole is described as a nonsteroidal aromatase inhibitor that inhibits estrogen synthesis.
It is insoluble in water.
The medicine is considered the first-line treatment in postmenopausal women with hormone receptor-positive and is used
for anti-estrogen therapy.
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It is used in the adjuvant treatment of rapid spreading hormone –dependant breast cancer.
Letrozole lowers the estrogen levels in postmenopausal women which reduces various types of breast tumors that need
estrogen to grow in the body.
It is used in the neo-adjuvant treatment of post-menopausal women with hormone receptor-positive and HER-2 –ve breast
cancer. In this case, Chemotherapy does not suit, and emergency surgery is not needed.
Monitor your luteinizing hormone (LH), follicle-stimulating hormone (FSH), and/or oestradiol levels before starting the
medicine.
Letrozole contains lactose therefore it is restricted to patients with rare hereditary galactose intolerance problems,
glucose-galactose malabsorption, and severe lactase deficiency.
Do not discontinue the course of medicine without your doctor’s advice, even if you feel good.
