the trio combination is an antiviral medicine. Efavirenz belongs to the non-nucleoside reverse transcriptase inhibitors
(NNRTIs) class, it inhibits the DNA dependant and RNA dependant DNA polymerase activities including the replication of
HIV-1.
and Lamivudine and Tenofovir disoproxil fumarate belong nucleoside and nucleotide transcriptase inhibitors (NRTIs)
class.
Lamivudine: It is a cytosine analog that is phosphorylated intracellularly to activate 5- triphosphate metabolite. It
terminates the DNA chain and inhibits DNA- dependant and DNA polymerase activities of reverse transcriptase.
Tenofovir DF: it is an analog of adenosine 5- monophosphate that blocks RNA dependant DNA polymerase resulting in the
inhibition of viral replication.
It inhibits the replication of HBV by blocking HBV polymerase.
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It is used for treating HIV infection that causes AIDS (Acquired Immune Deficiency Syndrome). It does not cure the
disease but blocks the virus or infections from spreading and decreases the complexity of the disease.
It boosts up your immune system that helps your body fight infections, and viruses existing in the body or entering the
body.
The medicine will be effective only when certain precautions like maintenance of hygiene, having protected sex, not
sharing personal things like razors, and toothbrushes, and avoiding blood contact with uninfected persons are followed.
Before taking the medicine, talk to your doctor to know about the after-effects, risks, and other clinical conditions of
the body.
In case of serious after-effects contact your medical help immediately to avoid complications getting worse.